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A review of the biologic effects, clinical efficacy, and safety of silicone elastomer sheeting for hypertrophic and keloid scar treatment and management.
by Berman B, Perez OA, Konda S, Kohut BE, Viera MH, Delgado S, Zell D, Li QDermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.].
Article Abstract:
Silicone elastomer sheeting is a medical device used to prevent the development of and improve the appearance and feel of hypertrophic and keloid scars. The precise mechanism of action of silicone elastomer sheeting has not been defined, but clinical trials report that this device is safe and effective for the treatment and prevention of hypertrophic and keloid scars if worn over the scar for 12 to 24 hours per day for at least 2 to 3 months. Some of the silicone elastomer sheeting products currently on the market are durable and adhere well to the skin. These products are an attractive treatment option because of their ease of use and low risk of adverse effects compared to other treatments, such as surgical excision, intralesional corticosteroid injections, pressure therapy, radiation, laser treatment, and cryotherapy. Additional controlled clinical trials with large patient populations may provide further evidence for the efficacy of silicone elastomer sheeting in the treatment and prevention of hypertrophic and keloid scars. The purpose of this article is to review the literature on silicone elastomer sheeting products and to discuss their clinical application in the treatment and prevention of hypertrophic and keloid scars.
A review of the biologic effects, clinical efficacy, and safety of silicone elastomer sheeting for hypertrophic and keloid scar treatment and management.
By: drls - Thu 11/22/2007 PM1. They note in table 1 that there are several types of silicone products available for scar prevention. However, I wish that they spoke more about the benefits or at least evidence for each one. For example, is silicone spray, or topical liquid silicone effective at all? In my hands - no... but these products get marketed along with silicone sheeting.
2. Before concluding, the authors state that "it is important to note that silicone elastomer sheeting should not be used on open wounds or unhealed skin." Why? The references offered for this statement do not support it. Is there any risk in doing this? Theoretical or proven?